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Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

A long-term goal in the field of restriction-modification enzymes has been to generate restriction endonucleases with novel sequence specificities by mutating or engineering existing enzymes. This will avoid the increasingly arduous task of extensive screening of bacteria and other microorganisms fo...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Kim, Y G, Cha, J, Chandrasegaran, S
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8577732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.3.1156
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