Deriving Therapies for Children with Primary CNS Tumors Using Pharmacokinetic Modeling and Simulation of Cerebral Microdialysis Data

The treatment of children with primary central nervous system (CNS) tumors continues to be a challenge despite recent advances in technology and diagnostics. In this overview, we describe our approach for identifying and evaluating active anticancer drugs through a process that enables rational tran...

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Detalhes bibliográficos
Main Authors: Jacus, M.O., Throm, S.L., Turner, D.C., Patel, Y.T., Freeman, B.B., Morfouace, M., Boulos, N., Stewart, C. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004667/
https://ncbi.nlm.nih.gov/pubmed/24269626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2013.11.010
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