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Id2 and Id3 Define the Potency of Cell Proliferation and Differentiation Responses to Transforming Growth Factor β and Bone Morphogenetic Protein

Transforming growth factors β (TGF-βs) inhibit growth of epithelial cells and induce differentiation changes, such as epithelial-mesenchymal transition (EMT). On the other hand, bone morphogenetic proteins (BMPs) weakly affect epithelial cell growth and do not induce EMT. Smad4 transmits signals fro...

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Autores principales: Kowanetz, Marcin, Valcourt, Ulrich, Bergström, Rosita, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC400464/
https://ncbi.nlm.nih.gov/pubmed/15121845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4241-4254.2004
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