IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways

Recent studies of the pathogenesis of rheumatoid arthritis (RA) have revealed that both synovial fibroblasts and T cells participate in the perpetuation of joint inflammation as dynamic partners in a mutual activation feedback, via secretion of cytokines and chemokines that stimulate each other. In...

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Detalhes bibliográficos
Main Authors: Hwang, Sue-Yun, Kim, Ju-Young, Kim, Kyoung-Woon, Park, Mi-Kyung, Moon, Youngmee, Kim, Wan-Uk, Kim, Ho-Youn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400429/
https://ncbi.nlm.nih.gov/pubmed/15059275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1038
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