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Directed Evolution of Multivalent Glycopeptides Tightly Recognized by HIV Antibody 2G12
[Image: see text] Herein, we report a method for in vitro selection of multivalent glycopeptides, combining mRNA display with incorporation of unnatural amino acids and “click” chemistry. We have demonstrated the use of this method to design potential glycopeptide vaccines against HIV. From librarie...
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| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004241/ https://ncbi.nlm.nih.gov/pubmed/24645849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500678v |
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