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Directed Evolution of 2G12-Targeted Nonamannose Glycoclusters by SELMA
Optimizing multivalency: Clusters of Man(9) glycans which are recognized by broadly-neutralizing anti-HIV antibody 2G12 have potential as HIV vaccines. However, optimal recognition by 2G12 requires optimal clustering of glycans. Using our recently described SELMA technique (SELection with Modified A...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896081/ https://ncbi.nlm.nih.gov/pubmed/24227340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201303848 |
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