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Directed Evolution of Multivalent Glycopeptides Tightly Recognized by HIV Antibody 2G12
[Image: see text] Herein, we report a method for in vitro selection of multivalent glycopeptides, combining mRNA display with incorporation of unnatural amino acids and “click” chemistry. We have demonstrated the use of this method to design potential glycopeptide vaccines against HIV. From librarie...
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| Main Authors: | , , , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Chemical
Society
2014
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| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004241/ https://ncbi.nlm.nih.gov/pubmed/24645849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500678v |
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