Lanean...
Detection of Protein–Protein Interactions by Proximity-Driven S(N)Ar Reactions of Lysine-Linked Fluorophores
[Image: see text] Critical protein–protein interactions are ubiquitous in biology. To provide a new method to detect these interactions, we designed and synthesized fluorinated bromopyronins as molecular probes. These electrophilic compounds rapidly react with amines via a S(N)Ar mechanism to form m...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Chemical
Society
2014
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004224/ https://ncbi.nlm.nih.gov/pubmed/24660775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501253b |
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