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Novel Acid-Activated Fluorophores Reveal a Dynamic Wave of Protons in the Intestine of Caenorhabditis elegans

Unlike the digestive systems of vertebrate animals, the lumen of the alimentary canal of C. elegans is unsegmented and weakly acidic (pH ~ 4.4), with ultradian fluctuations to pH > 6 every 45 to 50 seconds. To probe the dynamics of this acidity, we synthesized novel acid-activated fluorophores te...

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Detalhes bibliográficos
Main Authors: Bender, Aaron, Woydziak, Zachary R., Fu, Liqiang, Branden, Michael, Zhou, Zhenguo, Ackley, Brian D., Peterson, Blake R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600105/
https://ncbi.nlm.nih.gov/pubmed/23256594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300396j
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