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Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

The endoplasmic reticulum (ER) plays critical roles in the processing of secreted and transmembrane proteins. To deliver small molecules to this organelle, we synthesized fluorinated hydrophobic analogues of the fluorophore rhodol. These cell-permeable fluorophores are exceptionally bright, with qua...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Matthew Meinig, J., Fu, Liqiang, Peterson, Blake R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539238/
https://ncbi.nlm.nih.gov/pubmed/26118368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201504156
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