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Synthesis of Fluorinated Benzophenones, Xanthones, Acridones, and Thioxanthones by Iterative Nucleophilic Aromatic Substitution

Fluorination of fluorophores can substantially enhance their photostability and improve spectroscopic properties. To facilitate access to fluorinated fluorophores, bis(2,4,5-trifluorophenyl)methanone was synthesized by treatment of 2,4,5-trifluorobenzaldehyde with a Grignard reagent derived from 1-b...

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Autores principales: Woydziak, Zachary R., Fu, Liqiang, Peterson, Blake R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256751/
https://ncbi.nlm.nih.gov/pubmed/22111869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo202062f
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