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Non-classical antigen processing pathways are required for MHC class II-restricted direct tumor recognition by NY-ESO-1-specific CD4(+) T cells

Tumor antigen-specific CD4(+) T cells that directly recognize cancer cells are important for orchestrating antitumor immune responses at the local tumor sites. However, the mechanisms of direct MHC class II (MHC-II) presentation of intracellular tumor antigen by cancer cells are poorly understood. W...

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Detalhes bibliográficos
Main Authors: Matsuzaki, Junko, Tsuji, Takemasa, Luescher, Immanuel, Old, Lloyd J., Shrikant, Protul, Gnjatic, Sacha, Odunsi, Kunle
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004114/
https://ncbi.nlm.nih.gov/pubmed/24764581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0138
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