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Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer

NY-ESO-1 is a “cancer-testis” antigen expressed in epithelial ovarian cancer (EOC) and is among the most immunogenic tumor antigens defined to date. The NY-ESO-1 peptide epitope, ESO(157–170), is recognized by HLA-DP4-restricted CD4(+) T cells and HLA-A2- and A24-restricted CD8(+) T cells. To test w...

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Detalhes bibliográficos
Main Authors: Odunsi, Kunle, Qian, Feng, Matsuzaki, Junko, Mhawech-Fauceglia, Paulette, Andrews, Christopher, Hoffman, Eric W., Pan, Linda, Ritter, Gerd, Villella, Jeannine, Thomas, Bridget, Rodabaugh, Kerry, Lele, Shashikant, Shrikant, Protul, Old, Lloyd J., Gnjatic, Sacha
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937553/
https://ncbi.nlm.nih.gov/pubmed/17652518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703342104
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