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The BRRF1 Early Gene of Epstein-Barr Virus Encodes a Transcription Factor That Enhances Induction of Lytic Infection by BRLF1

The switch from the latent to the lytic form of Epstein-Barr virus (EBV) infection is mediated by expression of the viral immediate-early (IE) proteins, BZLF1 (Z) and BRLF1 (R). An EBV early protein, BRRF1 (Na), is encoded by the opposite strand of the BRLF1 intron, but the function of this nuclear...

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Autores principales: Hong, Gregory K., Delecluse, Henri-Jacques, Gruffat, Henri, Morrison, Thomas E., Feng, Wen-Hai, Sergeant, Alain, Kenney, Shannon C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC400377/
https://ncbi.nlm.nih.gov/pubmed/15113878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.4983-4992.2004
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