Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model

Most Epstein-Barr virus (EBV)-positive tumor cells contain one of the latent forms of viral infection. The role of lytic viral gene expression in EBV-associated malignancies is unknown. Here we show that EBV mutants that cannot undergo lytic viral replication are defective in promoting EBV-mediated...

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Autors principals: Hong, Gregory K., Gulley, Margaret L., Feng, Wen-Hai, Delecluse, Henri-Jacques, Holley-Guthrie, Elizabeth, Kenney, Shannon C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280209/
https://ncbi.nlm.nih.gov/pubmed/16254335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13993-14003.2005
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