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The Epstein-Barr Virus BMRF1 Gene Is Essential for Lytic Virus Replication
The Epstein-Barr virus (EBV) BMRF1 protein is a DNA polymerase processivity factor. We have deleted the BMRF1 open reading frame from the EBV genome and assessed the ΔBMRF1 EBV phenotype. ΔBMRF1 viruses were replication deficient, but the wild-type phenotype could be restored by BMRF1 trans-compleme...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2006
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472063/ https://ncbi.nlm.nih.gov/pubmed/16641300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.5078-5081.2006 |
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