Essential Role of Rta in Lytic DNA Replication of Epstein-Barr Virus

Two transcription factors, ZEBRA and Rta, switch Epstein-Barr virus (EBV) from the latent to the lytic state. While ZEBRA also plays an obligatory role as an activator of replication, it is not known whether Rta is directly required for replication. Rta is dispensable for amplification of an oriLyt-...

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Détails bibliographiques
Auteurs principaux: El-Guindy, Ayman, Ghiassi-Nejad, Maryam, Golden, Sean, Delecluse, Henri-Jacques, Miller, George
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536415/
https://ncbi.nlm.nih.gov/pubmed/23077295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01995-12
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