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Essential Role of Rta in Lytic DNA Replication of Epstein-Barr Virus

Two transcription factors, ZEBRA and Rta, switch Epstein-Barr virus (EBV) from the latent to the lytic state. While ZEBRA also plays an obligatory role as an activator of replication, it is not known whether Rta is directly required for replication. Rta is dispensable for amplification of an oriLyt-...

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Main Authors: El-Guindy, Ayman, Ghiassi-Nejad, Maryam, Golden, Sean, Delecluse, Henri-Jacques, Miller, George
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536415/
https://ncbi.nlm.nih.gov/pubmed/23077295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01995-12
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