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Lytic Induction Therapy for Epstein-Barr Virus-Positive B-Cell Lymphomas

A novel therapy for Epstein-Barr virus (EBV)-positive tumors involves the intentional induction of the lytic form of EBV infection combined with ganciclovir (GCV) treatment. Virally encoded kinases (thymidine kinase and BGLF4) which are expressed only during the lytic form of infection convert GCV (...

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Detalhes bibliográficos
Main Authors: Feng, Wen-hai, Hong, Gregory, Delecluse, Henri-Jacques, Kenney, Shannon C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369434/
https://ncbi.nlm.nih.gov/pubmed/14747554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1893-1902.2004
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