Lytic Induction Therapy for Epstein-Barr Virus-Positive B-Cell Lymphomas

A novel therapy for Epstein-Barr virus (EBV)-positive tumors involves the intentional induction of the lytic form of EBV infection combined with ganciclovir (GCV) treatment. Virally encoded kinases (thymidine kinase and BGLF4) which are expressed only during the lytic form of infection convert GCV (...

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Autors principals: Feng, Wen-hai, Hong, Gregory, Delecluse, Henri-Jacques, Kenney, Shannon C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC369434/
https://ncbi.nlm.nih.gov/pubmed/14747554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1893-1902.2004
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