Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

Aging is thought to be associated with increased molecular damage, but representative markers vary across conditions and organisms, making it difficult to assess properties of cumulative damage throughout lifespan. We used nontargeted metabolite profiling to follow age-associated trajectories of >...

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Bibliografiske detaljer
Main Authors: Avanesov, Andrei S, Ma, Siming, Pierce, Kerry A, Yim, Sun Hee, Lee, Byung Cheon, Clish, Clary B, Gladyshev, Vadim N
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2014
Fag:
Biochemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003482/
https://ncbi.nlm.nih.gov/pubmed/24843015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02077
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