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Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity

Lifespan varies dramatically among species, but the biological basis is not well understood. Previous studies in model organisms revealed the importance of nutrient sensing, mTOR, NAD/sirtuins, and insulin/IGF1 signaling in lifespan control. By studying life‐history traits and transcriptomes of 14 D...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Ma, Siming, Avanesov, Andrei S., Porter, Emily, Lee, Byung Cheon, Mariotti, Marco, Zemskaya, Nadezhda, Guigo, Roderic, Moskalev, Alexey A., Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052463/
https://ncbi.nlm.nih.gov/pubmed/29671950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12740
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