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On the cause of aging and control of lifespan: Heterogeneity leads to inevitable damage accumulation causing aging; control of damage composition and rate of accumulation define lifespan
What the causes of aging are and which factors define lifespan are key questions in the understanding of aging. Here, it is argued that cellular life involves (i) inevitable accumulation of damage resulting from imperfectness and heterogeneity of every cellular process, and (ii) dilution of damage w...
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804916/ https://ncbi.nlm.nih.gov/pubmed/22915358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200092 |
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