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Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

Aging is thought to be associated with increased molecular damage, but representative markers vary across conditions and organisms, making it difficult to assess properties of cumulative damage throughout lifespan. We used nontargeted metabolite profiling to follow age-associated trajectories of >...

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Bibliografische gegevens
Hoofdauteurs: Avanesov, Andrei S, Ma, Siming, Pierce, Kerry A, Yim, Sun Hee, Lee, Byung Cheon, Clish, Clary B, Gladyshev, Vadim N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003482/
https://ncbi.nlm.nih.gov/pubmed/24843015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02077
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