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CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines

AIM: Downregulation of androgen biosynthesis genes StAR (steroidogenic acute regulatory) and 3β-HSD (3β-hydroxysteroid dehydrogenase) contributes to low testosterone levels in hypoxic mice and is possibly related to increased expression of pro-inflammatory cytokines in the testis. The aim of this st...

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Detalhes bibliográficos
Main Authors: Zhang, Guo-lin, Yu, Feng, Dai, De-zai, Cheng, Yu-si, Zhang, Can, Dai, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003356/
https://ncbi.nlm.nih.gov/pubmed/22426698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.175
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