Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine

BACKGROUND: Hypoxia exposure initiates low serum testosterone levels that could be attributed to downregulated androgen biosynthesizing genes such as StAR (steroidogenic acute regulatory protein) and 3-beta-HSD (3-beta-hydroxysteroid dehydrogenase) in the testis. It was hypothesized that these abnor...

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Detalhes bibliográficos
Main Authors: Liu, Gui-Lai, Yu, Feng, Dai, De-Zai, Zhang, Guo-Lin, Zhang, Can, Dai, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276427/
https://ncbi.nlm.nih.gov/pubmed/22226148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-4
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