The Achilles heel of γ-secretase: can we contain Alzheimer's disease by reducing synthesis of β-amyloid?

Lignende værker

• γ-Secretase Modulators: Can We Combine Potency with Safety?
  af: Gijsen, Harrie J. M., et al.
  Udgivet: (2012)
• The RARγ Oncogene: An Achilles Heel for Some Cancers
  af: Brown, Geoffrey, et al.
  Udgivet: (2021)
• Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
  af: Kounnas, Maria Z., et al.
  Udgivet: (2010)
• In Vivo Manifestation of Notch Related Phenotypes in Zebrafish Treated with Alzheimer’s Amyloid Reducing γ-Secretase Inhibitors
  af: Yang, Ting, et al.
  Udgivet: (2010)
• Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease
  af: Huang, Xianhai, et al.
  Udgivet: (2012)