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Functional characterization of the NF-κB binding site in the human NOD2 promoter

Nucleotide-binding and oligomerization domain 2 (NOD2), a member of the NOD protein family, plays an important role in innate immunity. In response to pathogen attack, NOD2 stimulates cytokine and defensin production by activating nuclear factor (NF)-κB, a key transcription factor responsible for me...

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Detalhes bibliográficos
Main Authors: Hu, Chaofeng, Sun, Liping, Hu, Yiling, Lu, Daxiang, Wang, Huadong, Tang, Suisheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003228/
https://ncbi.nlm.nih.gov/pubmed/20436512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.16
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