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BRMS1 negatively regulates NF-κB–dependent uPA expression following recruitment of HDAC1 to the NF-κB binding site of the uPA promoter

The BRMS1 metastasis suppressor was recently shown to negatively regulate NF-κB signaling and down regulate NF-κB-dependent uPA expression. Here we confirm that BRMS1 expression correlates with reduced NF-κB DNA binding activity in independently derived human melanoma C8161.9 cells stably expressing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cicek, Muzaffer, Fukuyama, Ryuichi, Cicek, Mine S., Sizemore, Steven, Welch, Danny R., Sizemore, Nywana, Casey, Graham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756239/
https://ncbi.nlm.nih.gov/pubmed/19165610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-009-9235-1
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