Activation of Toll-like receptor 9 attenuates unilateral ureteral obstruction-induced renal fibrosis

AIM: To study whether activation of TLR9 by CpG-ODN would protect against and/or reverse renal fibrosis. METHODS: Animals were treated with CpG-ODN before or after undergoing a unilateral ureteral obstruction (UUO) procedure. The interstitial fibrotic lesions of obstructed kidneys were evaluated usi...

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Main Authors: Xin, Bing-mu, Wang, Xiao-xing, Jin, Wen, Yan, Hui-min, Cui, Bing, Zhang, Xiao-wei, Hua, Fang, Yang, Hong-zhen, Hu, Zhuo-wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002953/
https://ncbi.nlm.nih.gov/pubmed/21113175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.202
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