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Activation of Toll-like receptor 9 attenuates unilateral ureteral obstruction-induced renal fibrosis
AIM: To study whether activation of TLR9 by CpG-ODN would protect against and/or reverse renal fibrosis. METHODS: Animals were treated with CpG-ODN before or after undergoing a unilateral ureteral obstruction (UUO) procedure. The interstitial fibrotic lesions of obstructed kidneys were evaluated usi...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002953/ https://ncbi.nlm.nih.gov/pubmed/21113175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.202 |
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