Toll-Like Receptor Signaling and SIGIRR in Renal Fibrosis upon Unilateral Ureteral Obstruction

Innate immune activation via IL-1R or Toll-like receptors (TLR) contibutes to acute kidney injury but its role in tissue remodeling during chronic kidney disease is unclear. SIGIRR is an inhibitor of TLR-induced cytokine and chemokine expression in intrarenal immune cells, therefore, we hypothesized...

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Bibliographic Details
Main Authors: Skuginna, Veronika, Lech, Maciej, Allam, Ramanjaneyulu, Ryu, Mi, Clauss, Sebastian, Susanti, Heni Eka, Römmele, Christoph, Garlanda, Cecilia, Mantovani, Alberto, Anders, Hans-Joachim
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081345/
https://ncbi.nlm.nih.gov/pubmed/21544241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019204
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