Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus

The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes. Both of these mechanisms are known to be involved in autoimmuni...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lech, Maciej, Römmele, Christoph, Kulkarni, Onkar P., Susanti, Heni Eka, Migliorini, Adriana, Garlanda, Cecilia, Mantovani, Alberto, Anders, Hans-Joachim
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103530/
https://ncbi.nlm.nih.gov/pubmed/21637713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020118
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