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Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus

The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes. Both of these mechanisms are known to be involved in autoimmuni...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lech, Maciej, Römmele, Christoph, Kulkarni, Onkar P., Susanti, Heni Eka, Migliorini, Adriana, Garlanda, Cecilia, Mantovani, Alberto, Anders, Hans-Joachim
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103530/
https://ncbi.nlm.nih.gov/pubmed/21637713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020118
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