O-GlcNAc Transferase Is Critical for Transducin-like Enhancer of Split (TLE)-mediated Repression of Canonical Wnt Signaling

The Drosophila Groucho protein and its mammalian orthologues the transducin-like enhancers of split (TLEs) are critical transcriptional corepressors that repress Wnt and other signaling pathways. Although it is known that Groucho/TLEs are recruited to target genes by pathway-specific transcription f...

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Main Authors: Wu, Jing, Bowe, Damon B., Sadlonova, Andrea, Whisenhunt, Thomas R., Hu, Yong, Rustgi, Anil K., Nie, Yongzhan, Paterson, Andrew J., Yang, Xiaoyong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002120/
https://ncbi.nlm.nih.gov/pubmed/24616106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.553859
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