Mice with targeted inactivation of Ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability

OBJECTIVE: Lipid phosphate phosphatase 3 (LPP3), encoded by the PPAP2B gene, is an integral membrane enzyme that dephosphorylates, and thereby terminates, the G-protein-coupled receptor-mediated signaling actions of lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P). LPP3 is essential for...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Panchatcharam, Manikandan, Salous, Abdel K., Brandon, Jason, Miriyala, Sumitra, Wheeler, Jessica, Patil, Pooja, Sunkara, Manjula, Morris, Andrew J., Escalante-Alcalde, Diana, Smyth, Susan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001868/
https://ncbi.nlm.nih.gov/pubmed/24504738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302335
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky