A pro-convulsive carbamazepine metabolite: Quinolinic acid in drug resistant epileptic human brain

Drugs and their metabolites often produce undesirable effects. These may be due to a number of mechanisms, including biotransformation by P450 enzymes which are not exclusively expressed by hepatocytes but also by endothelial cells in brain from epileptics. The possibility thus exists that the poten...

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Detaylı Bibliyografya
Asıl Yazarlar: Ghosh, Chaitali, Marchi, Nicola, Hossain, Mohammed, Rasmussen, Peter, Alexopoulos, Andreas V., Gonzalez-Martinez, Jorge, Yang, Hu, Janigro, Damir
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001854/
https://ncbi.nlm.nih.gov/pubmed/22426401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.03.010
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