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Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains
PURPOSE: Brain drug bioavailability is regulated by the blood–brain barrier (BBB). It was recently suggested that cytochrome P450 (CYP) enzymes could act in concert with multidrug transporter proteins to regulate drug penetration and distribution into the diseased brain. The possibility that phase I...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805835/ https://ncbi.nlm.nih.gov/pubmed/23865846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12318 |
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