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Cellular localization and functional significance of CYP3A4 in the human epileptic brain

PURPOSE: Compelling evidence supports the presence of P450 enzymes (CYPs) in the central nervous system (CNS). However, little information is available on the localization and function of CYPs in the drug-resistant epileptic brain. We have evaluated the pattern of expression of the specific enzyme C...

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Detalhes bibliográficos
Main Authors: Ghosh, Chaitali, Marchi, Nicola, Desai, Nirav K., Puvenna, Vikram, Hossain, Mohammed, Gonzalez-Martinez, Jorge, Alexopoulos, Andreas V., Janigro, Damir
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056924/
https://ncbi.nlm.nih.gov/pubmed/21294720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02956.x
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