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Transgenic Expression of Constitutively Active RAC1 Disrupts Mouse Rod Morphogenesis
PURPOSE. Dominant-active RAC1 rescues photoreceptor structure in Drosophila rhodopsin-null mutants, indicating an important role in morphogenesis. This report assesses the morphogenetic effect of activated RAC1 during mammalian rod photoreceptor development using transgenic mice that express constit...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001786/ https://ncbi.nlm.nih.gov/pubmed/24651551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13649 |
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