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Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function
In nonphagocytic cells, Rac1 is a component of NADPH oxidase that produces reactive oxygen species [Ushio-Fukai M (2006) Sci STKE 2006:re8]. Rac1 is expressed abundantly in mammalian retinal photoreceptors, where it is activated in response to light stimuli [Balasubramanian N, Slepak VZ (2003) Curr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685247/ https://ncbi.nlm.nih.gov/pubmed/19470639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808940106 |
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