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Transgenic Expression of Constitutively Active RAC1 Disrupts Mouse Rod Morphogenesis

PURPOSE. Dominant-active RAC1 rescues photoreceptor structure in Drosophila rhodopsin-null mutants, indicating an important role in morphogenesis. This report assesses the morphogenetic effect of activated RAC1 during mammalian rod photoreceptor development using transgenic mice that express constit...

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Detalhes bibliográficos
Main Authors: Song, Hongman, Bush, Ronald A., Vijayasarathy, Camasamudram, Fariss, Robert N., Kjellstrom, Sten, Sieving, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001786/
https://ncbi.nlm.nih.gov/pubmed/24651551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13649
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