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Leptin-promoted cilia assembly is critical for normal energy balance

The majority of mammalian cells have nonmotile primary cilia on their surface that act as antenna-like sensory organelles. Genetic defects that result in ciliary dysfunction are associated with obesity in humans and rodents, which suggests that functional cilia are important for controlling energy b...

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Detalhes bibliográficos
Main Authors: Han, Yu Mi, Kang, Gil Myoung, Byun, Kyunghee, Ko, Hyuk Wan, Kim, Joon, Shin, Mi-Seon, Kim, Hyun-Kyong, Gil, So Young, Yu, Ji Hee, Lee, Bonghee, Kim, Min-Seon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001529/
https://ncbi.nlm.nih.gov/pubmed/24667636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69395
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