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Leptin-promoted cilia assembly is critical for normal energy balance
The majority of mammalian cells have nonmotile primary cilia on their surface that act as antenna-like sensory organelles. Genetic defects that result in ciliary dysfunction are associated with obesity in humans and rodents, which suggests that functional cilia are important for controlling energy b...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001529/ https://ncbi.nlm.nih.gov/pubmed/24667636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69395 |
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