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Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation
Affinity maturation of the antibody response is a fundamental process in adaptive immunity during which B-cells activated by infection or vaccination undergo rapid proliferation accompanied by the acquisition of point mutations in their rearranged immunoglobulin (Ig) genes and selection for increase...
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| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001017/ https://ncbi.nlm.nih.gov/pubmed/24795717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00170 |
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