Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy

Respiratory syncytial virus (RSV) can cause devastating lower respiratory tract infections in preterm infants or when other serious health problems are present. Immunoprophylaxis with palivizumab (Synagis), a humanized IgG(1) mAb, is the current standard of care for preventing RSV infection in at-ri...

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Detalhes bibliográficos
Main Authors: Hiatt, Andrew, Bohorova, Natasha, Bohorov, Ognian, Goodman, Charles, Kim, Do, Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Piedra, Pedro A., Gilbert, Brian E., Zeitlin, Larry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000855/
https://ncbi.nlm.nih.gov/pubmed/24711420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402458111
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