Plant-based Production of Two Chimeric Monoclonal IgG Antibodies Directed against Immunodominant Epitopes of Vibrio cholerae Lipopolysaccharide

We have produced and characterized two chimeric IgG(1) monoclonal antibodies that bind different immunodominant epitopes on Vibrio cholerae lipopolysaccharide (LPS). MAb 2D6 IgG(1) recognizes Ogawa O-polysaccharide antigen, while mAb ZAC-3 IgG(1) recognizes core/lipid A moiety of Ogawa and Inaba LPS...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Levinson, Kara J., Giffen, Samantha R., Pauly, Michael H., Kim, Do H., Bohorov, Ognian, Bohorova, Natasha, Whaley, Kevin J., Zeitlin, Larry, Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458452/
https://ncbi.nlm.nih.gov/pubmed/25865265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2015.04.001
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