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Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces

Reprogramming receptors to artificially respond to light has strong potential for molecular studies and interrogation of biological functions. Here, we design a light-controlled ionotropic glutamate receptor by genetically encoding a photoreactive unnatural amino acid (UAA). The photo–cross-linker p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhu, Shujia, Riou, Morgane, Yao, C. Andrea, Carvalho, Stéphanie, Rodriguez, Pamela C., Bensaude, Olivier, Paoletti, Pierre, Ye, Shixin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000820/
https://ncbi.nlm.nih.gov/pubmed/24715733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318808111
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