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Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces
Reprogramming receptors to artificially respond to light has strong potential for molecular studies and interrogation of biological functions. Here, we design a light-controlled ionotropic glutamate receptor by genetically encoding a photoreactive unnatural amino acid (UAA). The photo–cross-linker p...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000820/ https://ncbi.nlm.nih.gov/pubmed/24715733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318808111 |
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