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Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats

BACKGROUND: Berberine (BBR), a natural plant extract, has been shown to improve lipid metabolism. However, its effects on PCSK9, a key factor involving in the lipid metabolism, have not yet been evaluated in vivo. The aim of the present study was to investigate the effect of BBR on PCSK9 expression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jia, Yan-Jun, Xu, Rui-Xa, Sun, Jing, Tang, Yue, Li, Jian-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000533/
https://ncbi.nlm.nih.gov/pubmed/24755036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-103
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