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Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a novel biomarker of LDL clearance and a therapeutic target of cardiovascular disease. We examined the effects of aerobic exercise training in modulating PCSK9 abundance and hepatic sterol regulation in high-fat-fed C57BL/6 mice. Mice (n = 8)...

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Detalhes bibliográficos
Main Authors: Wen, Shin, Jadhav, Kavita S., Williamson, David L., Rideout, Todd C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703876/
https://ncbi.nlm.nih.gov/pubmed/23862065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/908048
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