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Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats

BACKGROUND: Berberine (BBR), a natural plant extract, has been shown to improve lipid metabolism. However, its effects on PCSK9, a key factor involving in the lipid metabolism, have not yet been evaluated in vivo. The aim of the present study was to investigate the effect of BBR on PCSK9 expression...

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Main Authors: Jia, Yan-Jun, Xu, Rui-Xa, Sun, Jing, Tang, Yue, Li, Jian-Jun
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000533/
https://ncbi.nlm.nih.gov/pubmed/24755036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-103
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